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Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by inflammation and ulceration of the colonic mucosa. It primarily affects the rectum and may extend proximally in a continuous manner throughout the colon. The etiology of ulcerative colitis remains largely unknown, although it is believed to result from a combination of genetic predisposition, environmental factors, and dysregulation of the immune system. The incidence of UC has been observed to be increasing globally, particularly in westernized societies, making it a significant public health concern. The clinical presentation of ulcerative colitis can vary greatly among individuals, ranging from mild symptoms to severe complications. Common symptoms include abdominal pain, diarrhea often mixed with blood or mucus, tenesmus, and weight loss. The disease course can be intermittent with periods of remission and exacerbation. Complications may arise, including colonic perforation, toxic megacolon¡¦(»ý·«)


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Regist : 2024-10-09
Update : 2024-10-09
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