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Type 1, Type 2, Type 3, and Type Among these, Types 1 and 3 are most commonly associated with pneumonia and other lower respiratory tract infections. These viruses primarily infect the respiratory epithelium, leading to inflammation and an array of clinical symptoms. The pathogenesis of Parainfluenza virus-induced pneumonia typically involves the initial viral entry into the respiratory tract, where it attaches to and infects epithelial cells. This viral replication elicits a host immune response, which, although necessary for controlling the infection, can also contribute to tissue damage and exacerbation of symptoms. Clinically, this may present as cough, wheezing, difficulty breathing, and fever accompanied by the characteristic findings of pneumonia on imaging studies, such as infiltrates in the lungs. Moreover, the infection is often complicated by secondary bacterial infections, which can further complicate the clinical picture and lead to more severe respiratory dist¡¦(»ý·«)
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