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�뿇 �빐�룆�씠���, �쟾�궗�맂 mRNA�뒗 �빑�쓣 鍮좎졇 �굹��� �꽭�룷吏덈줈 鍮좎졇�굹��� ribosome�뿉 遺�李⑺븯寃� �릺怨�, mRNA�쓽 �젙蹂� �빐�룆�븳 �썑, 媛� codon�뿉 �빐�떦�븯�뒗 �븘誘몃끂�궛(aa)瑜� tRNA媛� �슫諛섑븯怨� r RNA媛� 怨꾩냽 �뿰寃곗떆耳� �떒諛깆쭏�쓣 �빀�꽦�븯�뒗 怨쇱젙�씠�떎. 利�, DNA�궡�뿉 �븫�샇�솕�릺�뼱 �엳�뒗 �젙蹂댁뿉 �뵲�씪�꽌 �떒諛깆쭏�씠 �빀�꽦�릺�뒗 寃껋씠�떎. 洹� �젙蹂�(�쑀�쟾�젙蹂�)�뒗 媛쒖떆, 醫낃껐 諛� �븘誘몃끂�궛�쓣 �쐞�븳 寃� �벑 64媛�吏�濡쒖꽌 媛� �젙蹂대뒗 3媛쒖쓽 �뿼湲곕줈 援ъ꽦�릺�뼱 �엳�떎. ���遺�遺꾩쓽 �븘誘몃끂�궛��� �븯�굹 �씠�긽�쓽 肄붾룉�쓣 媛�吏��뒗�뜲, �븯�굹�쓽 �븘誘몃끂媛꾩뿉 �빐�떦�릺�뒗 �뿬�윭 媛�吏� 肄붾룉��� ���媛� 3踰덉㎏ �뿼湲곕쭔 �떎瑜대떎.
�뿇 由щ낫�넑��� �몢 媛쒖쓽 �냼�떒�쐞濡� �릺�뼱 �엳�뼱硫� �떒諛깆쭏怨� rRNA(ribosomal RNA, 由щ낫�넑RNA)濡� 援ъ꽦�릺�뼱�엳�떎. small subunit�뿉�뒗 mRNA寃고빀遺��쐞媛� �엳怨�, large subunit�뿉�뒗 tRNA�쓽 寃고빀遺��쐞媛� �엳�떎. tRNA寃고빀遺��쐞�뒗 P site��� A site媛� �엳�떎. P site�뿉�꽌�뒗 �뤃由ы렔�떚�뱶媛� �떊�옣�릺硫�, A site�뿉�꽌�뒗 �깉濡� 泥④���븷 �븘誘몃끂�궛�쓣 �슫諛섑븯�뒗 tRNA媛� 寃고빀�븳�떎. �븘�떎�솕�맂 tRNA遺꾩옄�뿉�뒗 aminoacyl tRNA synthetase�뿉 �쓽�븯�뿬 洹몄씠 3��� 留먮떒�뿉 �븯�굹�쓽 �븘誘몃끂�궛�씠 寃고빀�릺�뼱 �엳�떎.
�뿇 �빐�룆�쓽 怨쇱젙
�뫒 媛쒖떆(initation)
- 由щ낫�넑�쓽 �냼�떒�쐞泥�, 媛쒖떆 tRNA 洹몃━怨� mRNA瑜� �븳�뜲 寃고빀�떆�궎�뒗 怨쇱젙
- 媛쒖떆肄붾룉��� methionin�쓣 coding �븯�뒗 AUG : �쑀�쟾�옄�쓽 �빐�룆 �떆�옉�젏
- 40S 諛� 80S 媛쒖떆蹂듯빀泥댁쓽 �삎�꽦 : mRNA, ribosome, 媛쒖떆 tRNA 諛� 湲고�� 媛쒖떆�씤�옄 (initiation factor)�뱾�씠 寃고빀
�뫓 �뿰�옣(elongation)
- �븘誘몃끂�븘�떎 tRNA �삎�꽦 : �븘誘몃끂�궛怨� tRNA媛� 寃고빀�븯�뒗�뜲�뒗 aminoacyl-tRNA synthase �슚�냼�뿉 �쓽�븯�뿬 tRNA 留먮떒�뿉 �쐞移섑븳 3�뼚�뼚-OH湲곗�� �븘誘몃끂�궛�쓽 -COOH�뿉 �뿉�뒪�뀒瑜� ���(�깮�왂)
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